一. Chemotherapy or radiotherapy, as one of the main methods to treat tumors, often causes a variety of adverse reactions and seriously affects the life quality of patients with tumors.
A randomized, double-blind, multicenter clinical study of Yangzheng Xiaoji Capsules combined with interventional chemotherapy in the treatment of primary liver cancer.
Academician Yu Jinming initiated the controlled clinical study of Yangzheng Xiaoji Capsules combined with chemotherapy in the treatment of advanced lung cancer。
Controlled Clinical Study of Yangzheng Xiaoji Capsules Combined with Chemotherapy in the Treatment of Breast Cancer
Yangzheng Xiaoji Capsules was recommended by the Consensus on Diagnosis and Treatment of Breast Cancer with Integrated Traditional Chinese Medicine and Western Medicine for the treatment of breast cancer。
二 . Yangzheng Xiaoji Capsules inhibits angiogenesis and tumor growth
Neovascularization Promotes Tumor Growth and Metastasis
Several basic series studies of Yangzheng Xiaoji in collaboration with Cardiff University in UK, have confirmed that Yangzheng Xiaoji can inhibit tumor progression through a variety of ways
Yangzheng Xiaoji Capsules Inhibits Angiogenesis in Tumors
Yangzheng Xiaoji Capsules Inhibits Tumor Cell Adhesion and Migration
Yangzheng Xiaoji Significantly Inhibits Tumor Growth and Exerts a Synergistic Effect in Combined Use
- The combined use of DME25 and FAK inhibitor significantly inhibited osteosarcoma tumor growth after 3 weeks. No obvious side effects were observed throughout the study.
- The combined use of Yangzheng Xiaoji and cMET kinase inhibitor PHA665752 showed a more significant inhibitory effect on the growth of tumor in the A549 tumor model.
Summary
Yangzheng Xiaoji Capsules is an antineoplastic drug developed by exploring the pathological mechanism of malignant tumors in TCM using the theory of collateral diseases.
Improve patient’s medication compliance: Full dose/complete course of treatment - improving efficacy and reducing recurrence。
Among the various factors affecting the therapeutic effect of drugs, failure of medication compliance by the patients has received an increasing concern from doctors!
Patient non-compliance (arbitrarily changing the dose/reducing the frequency of medication/self-discontinuation, etc.), will affect the therapeutic effect even using the best therapy
A positive dose-response relationship is observed within the range of normal therapeutic dose (Refer to 1-2 dose-response plot)
Studies have shown that administration at full dose and complete course of treatment can improve the efficacy
After administration of Yangzheng Xiaoji for 4 weeks at a dose of 12 capsules a day, the short-term remission rate of liver cancer was 22.4% (15.3% for chemotherapy alone). The response rate in treating TCM symptoms was 65.2% (36.1% for chemotherapy alone). The increased stablility rate of life quality was 85% (76.7% for chemotherapy alone). The increased stablity rate of body weight was 78.3% (70.8% for chemotherapy alone) *
After administration of Yangzheng Xiaoji at a dose of 12 capsules a day, the short-term remission rate of liver cancer was 23.3% (14% for interventional chemotherapy alone). The response rate in treating TCM symptoms was 65.3% (33% for interventional chemotherapy alone). The life quality and body weight increased by 54.3% and 34.3%, respectively (38% and 22.2% for interventional chemotherapy alone); * *
Prescription advice: For Yangzheng Xiaoji, 4 capsules per time, 3 times a day, with 4 weeks as one course of treatment, for oral administration. Cancer patients requiring long-term treatment can take it for a long time
Strength and packaging: 0.39 g per capsule, 36 capsules per carton.