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Why The Application Research of Shensong Yangxin Capsule won the first prize?

Jun 21,2023 | YILING

Why The Application Research of Shensong Yangxin Capsule in the Treatment of Arrhythmia won the first prize?

1. Theoretical innovation: Featured by simultaneously treating tachyarrhythmia and bradycardia, open up a new way to treat arrhythmia from "rhythm control" to "rhythm regulation".

2. Definite effect: Firstly carried out the prospective, randomized, double-blind, multicenter evidence-based study in China, result proved that Shensong Yangxin Capsule can effectively treat premature beats, atrial fibrillation and bradyarrhythmia, offering an exact treatment option for refractory diseases such as ventricular premature beats with heart failure and sinus bradycardia with ventricular premature beats.

3. High safety: Compared with antiarrhythmic conventional medicine, Shensong Yangxin Capsule has obvious safety advantages without arrhythmogenic side effects.

4. Unique mechanism: According to experimental studies, as Shensong Yangxin Capsules can blockade ion channels and regulate non-ion channels, it can effectively treat arrhythmia by improving microcirculation, reversing cardiac remodeling, electrical remodeling and neural remodeling.

Shensong Yangxin Capsules--Integrated Regulation Dispel Cold, Clear Heart Heat, Tonify Spirit and Promote Channels

Won the second prize of 2009 National Science and Technology Progress Award

Shensong Yangxin is Scientifically Formulated and Ingeniously Compatible

Component

Efficacy

Pharmacology

Indicating symptoms

Panax ginseng,

Ophiopogon japonicus,

Schisandra chinensis

Replenishing Qi

Nourishing Yin

Regulat autonomic nerve function;

Enhance myocardial contractility and cardiac output;

Improve coronary blood flow after myocardial ischemia; Inhibit myocardial K+-Na+ -atpase activity;

Improve cardiac physiological function and sinoatrial node tissue function.

Palpitation, Shortness of breath, Fatigue.

Ziziphi Spinosae Semen,

Os Draconis

Tranquilize
mind

Sedative, hypnotic, anticonvulsant;

Improve myocardial ischemia;

Improve hypoxia resistance;

Insomnia, Dreaminess

Salviae miltiorrhiza,

Paeoniae Radix Rubra,

Eupolyphaga sinensis,Nardostachys chinensis Batal

Promote blood circulation

Expand coronary artery;

Increase coronary blood flow;

Reduce platelet adhesion and aggregation;

Anticoagulation;

Fatigue, Dizziness

Taxilli Herba,

Cornus officinalis

Replenish liver and kidney,

Condense heart-qi

Anti-inflammatory and analgesia, Inhibit Ca2+ influx, protect cardiovascular;

Cardiotonic effect: improve cardiac function, increase myocardial contractility and cardiac output, improve cardiac work efficiency;

Chest tightness, Shortness of breath

Coptidis Rhizoma

Clear heart fire,

Tranquilize
mind

Positive inotropic effect on myocardium;

Prolong action potential duration and functional refractory period;

Inhibit delayed outward potassium current and tail current. Sedation and analgesia;

Palpitation, Restlessness

 

Shensong Yangxin Capsule Has Both Multi-ion Channel and Non-ion Channel Integration and Regulation Effects

TCM Vessel Collateral Theory and Its Application won the first prize of the National Science and Technology Progress Award in 2019

 

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