Why The Application Research of Shensong Yangxin Capsule won the first prize?
Jun 21,2023 | YILING
Why The Application Research of Shensong Yangxin Capsule in the Treatment of Arrhythmia won the first prize?
1. Theoretical innovation: Featured by simultaneously treating tachyarrhythmia and bradycardia, open up a new way to treat arrhythmia from "rhythm control" to "rhythm regulation".
2. Definite effect: Firstly carried out the prospective, randomized, double-blind, multicenter evidence-based study in China, result proved that Shensong Yangxin Capsule can effectively treat premature beats, atrial fibrillation and bradyarrhythmia, offering an exact treatment option for refractory diseases such as ventricular premature beats with heart failure and sinus bradycardia with ventricular premature beats.
3. High safety: Compared with antiarrhythmic conventional medicine, Shensong Yangxin Capsule has obvious safety advantages without arrhythmogenic side effects.
4. Unique mechanism: According to experimental studies, as Shensong Yangxin Capsules can blockade ion channels and regulate non-ion channels, it can effectively treat arrhythmia by improving microcirculation, reversing cardiac remodeling, electrical remodeling and neural remodeling.
Shensong Yangxin Capsules--Integrated Regulation Dispel Cold, Clear Heart Heat, Tonify Spirit and Promote Channels
Won the second prize of 2009 National Science and Technology Progress Award
Shensong Yangxin is Scientifically Formulated and Ingeniously Compatible
Component |
Efficacy |
Pharmacology |
Indicating symptoms |
Panax ginseng, Ophiopogon japonicus, Schisandra chinensis |
Replenishing Qi Nourishing Yin |
Regulat autonomic nerve function; Enhance myocardial contractility and cardiac output; Improve coronary blood flow after myocardial ischemia; Inhibit myocardial K+-Na+ -atpase activity; Improve cardiac physiological function and sinoatrial node tissue function. |
Palpitation, Shortness of breath, Fatigue. |
Ziziphi Spinosae Semen, Os Draconis |
Tranquilize |
Sedative, hypnotic, anticonvulsant; Improve myocardial ischemia; Improve hypoxia resistance; |
Insomnia, Dreaminess |
Salviae miltiorrhiza, Paeoniae Radix Rubra, Eupolyphaga sinensis,Nardostachys chinensis Batal |
Promote blood circulation |
Expand coronary artery; Increase coronary blood flow; Reduce platelet adhesion and aggregation; Anticoagulation; |
Fatigue, Dizziness |
Taxilli Herba, Cornus officinalis |
Replenish liver and kidney, Condense heart-qi |
Anti-inflammatory and analgesia, Inhibit Ca2+ influx, protect cardiovascular; Cardiotonic effect: improve cardiac function, increase myocardial contractility and cardiac output, improve cardiac work efficiency; |
Chest tightness, Shortness of breath |
Coptidis Rhizoma |
Clear heart fire, Tranquilize |
Positive inotropic effect on myocardium; Prolong action potential duration and functional refractory period; Inhibit delayed outward potassium current and tail current. Sedation and analgesia; |
Palpitation, Restlessness
|
Shensong Yangxin Capsule Has Both Multi-ion Channel and Non-ion Channel Integration and Regulation Effects
TCM Vessel Collateral Theory and Its Application won the first prize of the National Science and Technology Progress Award in 2019