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How to Inhibits Angiogenesis and Tumor Growth?

Jun 26,2023 | YILING

Neovascularization Promotes Tumor Growth and Metastasis.

   The transformation of angiogenesis is a prerequisite for the development of invasive tumors in the pre-malignant stage. Angiogenesis not only provides nutrients for tumor growth, but also provides a huge surface area of leaky vessels with incomplete basement membrane for tumor cell intravasation; tumor cells spread to distal organs and initially exist in the form of avascular dormant micrometastasis. Secondary angiogenesis and tumor growth will lead to extensive tumor metastasis.

   Several basic series studies of Yangzheng Xiaoji in collaboration with Cardiff University in UK, have confirmed that Yangzheng Xiaoji can inhibit tumor progression through a variety of ways.

Yangzheng Xiaoji Capsules Inhibits Angiogenesis in Tumors.


Yangzheng Xiaoji Capsules Inhibits Tumor Cell Adhesion and Migration.


Yangzheng Xiaoji Significantly Inhibits Tumor Growth and Exerts a Synergistic Effect in Combined Use

  The combined use of DME25 and FAK inhibitor significantly inhibited osteosarcoma tumor growth after 3 weeks. No obvious side effects were observed throughout the study.

  The combined use of Yangzheng Xiaoji and cMET kinase inhibitor PHA665752 showed a more significant inhibitory effect on the growth of tumor in the A549 tumor model.